Director, HCP Professional Promotion Marketing

Legend Biotech is seeking a Director, HCP Professional Promotion Marketing as part of the Commercial team based in Bridgewater, NJ.

Role Overview

Legend Biotech is seeking a senior marketing leader to drive HCP professional promotion for CARVYKTI^® (ciltacabtagene autoleucel; cilta-cel), a BCMA-directed, bivalent CAR-T cell therapy approved for relapsed or refractory multiple myeloma. This is a high-impact role at the commercial center of one of the most scientifically significant therapies in hematologic oncology.

The person in this role will own HCP-facing professional promotion strategy and execution for CARVYKTI in the US, spanning message development and campaign delivery through field force enablement and agency management. They will operate within a co-promotion alliance with Johnson & Johnson, requiring sophisticated cross-organizational collaboration alongside clear internal accountability. The role demands both scientific fluency and commercial judgment: CARVYKTI’s clinical profile, including data from the CARTITUDE program, is compelling, and communicating it accurately and persuasively to hematologist-oncologists across academic and community settings is the core of this job.

This position requires a candidate who is comfortable with the operational complexity specific to CAR-T cell therapies, including authorized treatment center dynamics, patient identification and referral pathways, and the leukapheresis-to-infusion logistics that shape the prescriber experience. It also requires someone who can navigate a competitive CAR-T landscape with scientific rigor and strategic clarity.

Key Responsibilities

Strategy and brand planning

• Lead the development of annual HCP professional promotion marketing plans grounded in customer insights, competitive intelligence, and the evolving CARVYKTI evidence base.
• Translate CARTITUDE program data and the broader multiple myeloma treatment landscape into differentiated positioning and messaging for community and academic hematologist-oncologists, with language that will hold up through medical, legal, and regulatory review.
• Monitor competitive dynamics, including other BCMA-directed CAR-T therapies and bispecific antibodies, and translate signals into actionable strategic recommendations.
• Identify and prioritize market opportunities, with particular focus on patient identification, community oncologist education, and authorized treatment center support.

J&J alliance and cross-functional execution

• Partner with Johnson & Johnson across all aspects of HCP professional promotion, including message development, content creation, agency alignment, and tactical execution, while maintaining clear accountability for Legend’s strategic priorities.
• Collaborate with nurse, NPP/omnichannel, patient marketing, and market development leads to ensure consistency across all HCP and patient-facing marketing functions.
• Work with the Key Customer Engagement Team to incorporate HCP insights into strategy and execution.
• Partner with insights and analytics to initiate and interpret market research that deepens understanding of the CARVYKTI customer, the myeloma disease environment, and the CAR-T treatment landscape.
• Collaborate with sales training and the head of sales to equip the field force with strategy, messaging, and materials that are accurate, compelling, and field-ready.

Agency and budget management

• Manage professional promotion agency partners to deliver plans and tactics on time and within budget.
• Own HCP key performance indicators and develop reporting frameworks to evaluate and measure promotional effectiveness and ROI.
• Prepare and deliver presentations to senior leadership and other internal and external audiences.

Compliance and regulatory adherence

• Ensure all promotional activities comply with applicable laws, regulations, and FDA promotional guidelines governing commercial interactions with healthcare professionals and other business partners.
• Lead medical, legal, and regulatory review submissions for professional promotion materials, maintaining documentation standards and incorporating review feedback efficiently.

Requirements

• BA/BS required; MBA or advanced science degree a plus.
• Significant pharmaceutical marketing experience, with meaningful time in HCP-facing brand roles; oncology required.
• Deep knowledge of hematology/oncology strongly preferred; familiarity with multiple myeloma treatment paradigms, BCMA-directed therapeutics, or CAR-T/cellular therapy is a meaningful differentiator.
• Experience operating within co-promotion alliances or complex multi-stakeholder commercial environments preferred.
• Familiarity with the access and operational dynamics of specialty cell therapies, including authorized treatment center infrastructure and the leukapheresis-to-infusion patient journey, is a plus.
• Demonstrated ability to translate complex clinical data into clear, compelling, and compliant HCP-facing communications.
• Strong strategic thinking: able to synthesize competitive intelligence, market data, and customer insights into actionable brand strategy.
• Proven cross-functional leadership: comfortable influencing without authority across alliance partners, internal functions, and agency teams.
• Exceptional written and oral communication skills, including executive-level presentation capability.
• Self-directed and highly accountable, with strong project management skills and the ability to manage multiple priorities simultaneously.
• Entrepreneurial orientation: comfortable operating in fast-moving, complex environments where not all answers are defined.
• Willingness to travel approximately 25% as required by business need.

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